Patients with a bipolar disorder show slightly increased levels of inflammatory markers in their blood. These inflammatory markers could potentially lead to brain damage. We suspect that this inflammation potentially contributes to a more severe disease progression, more cognitive impairments and therapy resistance. In this project we aim to determine the role of inflammatory disturbances associated with:

• the severity of depression or manic symptoms,

• the severity of cognitive impairments,

• the severity of disease progression.  

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Funding: PZ Duffel and Johnson&Johnson (Janssen Pharmaceutica)

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